Anti-SAG Antibody

Raised in rabbit against the retinal S-arrestin (also called arrestin-1) protein, this polyclonal IgG reagent from Antibodies.com supports vision science and ocular immunology research. SAG participates in terminating the phototransduction cascade within rod and cone outer segments, and is recognized as an autoantigen in mouse models of experimental autoimmune uveoretinitis and retinal degeneration. The unconjugated antibody is supplied at a 200 µl size and validated for western blot detection of mouse SAG, where it recognizes a band near the expected ~45 kDa molecular weight of arrestin-1. Host species is rabbit, clonality polyclonal, isotype IgG, with reactivity directed against mouse samples, providing a focused reagent for immunoblotting of murine retinal lysates and related photoreceptor signaling studies.