Anti-Saccharomyces cerevisiae Antibody

Produced in rabbit as a polyclonal Ig fraction, this Antibodies.com reagent targets mannan epitopes of the Saccharomyces cerevisiae cell wall and is widely used in immunology and gastroenterology research. ASCA (anti-Saccharomyces cerevisiae antibodies) serve as established serological markers that aid in the differential diagnosis of Crohn's disease versus ulcerative colitis within inflammatory bowel disease panels, and the same specificity supports studies of fungal antigen recognition, mucosal barrier function, and host-microbe interactions.

Supplied unconjugated in a 500 µl vial, the antibody is validated for ELISA, immunofluorescence assay (IFA), Western blot, and immunohistochemistry on relevant tissue and serum specimens. For handling, the reagent should be refrigerated upon receipt, protected from light, and aliquoted on first use to limit freeze-thaw cycles and preserve binding activity across longitudinal studies.