Anti-SAA1 Antibody

A rabbit polyclonal IgG antibody from Antibodies.com that recognizes human Serum Amyloid A1 (SAA1), an acute-phase apolipoprotein synthesized by hepatocytes in response to inflammatory cytokines such as IL-1, IL-6 and TNF. Supplied unconjugated in a 50 µl volume and validated for Western blot, the reagent detects the approximately 12 kDa SAA1 protein in human-derived samples, including cell lysates, tissue homogenates and conditioned media. SAA1 serves as a sensitive circulating biomarker for acute inflammation, microbial infection, trauma and chronic conditions such as secondary (AA) amyloidosis, and is frequently monitored alongside CRP in clinical and experimental studies. The polyclonal format increases the likelihood of recognizing multiple epitopes on the mature SAA1 polypeptide and its precursor, supporting reproducible band detection across different lysate preparations and reducing the risk of signal loss from minor epitope variation. Researchers investigating the acute-phase response, inflammatory disease models, vaccine response, atherosclerosis, or AA amyloidosis pathways can apply this reagent to compare SAA1 expression between healthy and inflamed states, or between treated and untreated cohorts, in western blot workflows.