Anti-S100A8 Antibody

Calcium-binding proteins of the S100 family serve as informative markers in inflammation and myeloid-cell biology, and S100A8 (also known as calgranulin A or MRP8) is widely studied for its role pairing with S100A9 to form the calprotectin heterodimer. Antibodies.com supplies this rabbit polyclonal primary antibody for Western blot, immunohistochemistry, and immunofluorescence work on Human and Rat samples, supplied as 100 µl of unconjugated antisera in a single-use vial format. Researchers use the reagent to probe neutrophil and monocyte activation, track inflammatory signaling in tissue sections, and characterize disease models ranging from rheumatoid arthritis and inflammatory bowel disease to tumor microenvironment studies where calprotectin levels have prognostic value. Polyclonal recognition of conserved epitopes in the EF-hand calcium-binding domain gives the reagent flexibility across denatured and native preparations, supporting reproducible detection in cell lysates, formalin-fixed paraffin-embedded sections, and cultured myeloid cell lines.