Anti-S100A11 Antibody

The Antibodies.com primary polyclonal reagent specifically detects human S100A11, a calcium-binding protein implicated in epithelial differentiation, cytoskeletal remodeling, and certain cancer cell migration pathways. Produced in rabbit and supplied unconjugated at 100 µl, this polyclonal antibody is validated across multiple imaging and protein-detection workflows including Western blot, immunohistochemistry, and immunofluorescence.

S100A11, also known as calgizzarin, belongs to the S100 family of EF-hand calcium-binding proteins and is broadly expressed in human tissues such as skin, kidney, and several epithelial linings, where it associates with annexin A2 and contributes to membrane repair and receptor trafficking. Researchers investigating squamous cell carcinomas, breast tumors, or inflammatory skin conditions commonly probe S100A11 expression patterns to study tumor-stroma interactions or keratinocyte biology.

Each vial is delivered as a liquid polyclonal antiserum suitable for immunolabeling of fixed cells, tissue sections, and denatured protein extracts. The unconjugated format allows users to couple the antibody to fluorophores, HRP, or biotin according to their experimental design, supporting flexibility for double-staining protocols or signal amplification strategies in research use only settings.