Anti-RyR-2 Antibody

Raised in rabbit as a polyclonal reagent against the cardiac ryanodine receptor, this unconjugated primary antibody from Antibodies.com targets the RyR-2 calcium release channel that mediates sarcoplasmic reticulum Ca2+ efflux during cardiac excitation-contraction coupling. The immunogen-derived polyclonal population supports detection of the ~565 kDa RyR-2 protein across human, mouse, and rat samples, which is particularly useful in cardiovascular research into catecholaminergic polymorphic ventricular tachycardia, arrhythmogenic right ventricular cardiomyopathy, and heart failure models.

Validated uses include Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows. The 100 µL aliquot is supplied as a liquid antiserum fraction and should be stored refrigerated at 4°C for short-term use, or frozen in working aliquots to limit freeze-thaw cycles. Intended for research use only.