Anti-RXFP3 Antibody

This unconjugated, rabbit polyclonal reagent from Antibodies.com is supplied as a 100 µL liquid aliquot and was raised against Relaxin Family Peptide Receptor 3, a class A G-protein coupled receptor that selectively binds the neuropeptide relaxin-3 (INSL7) and is best known for its roles in central nervous system signaling.

Validated applications include Western blot and immunohistochemistry on samples from human and mouse origin. In tissue, RXFP3 expression is concentrated in brain regions such as the paraventricular and supraoptic nuclei of the hypothalamus, the hippocampus, and the dorsal raphe, where the receptor contributes to regulation of stress axis activity, feeding behavior, arousal, and memory. The polyclonal format allows recognition of multiple epitopes on the target, supporting IHC localization in fixed brain sections and Western blot detection of receptor bands from transfected cell lines and primary tissue lysates.

For storage, keep the vial refrigerated at 4 °C for short term use; for longer term storage, freeze aliquots at -20 °C and avoid repeated freeze-thaw cycles by preparing single-use working portions. The reagent is intended for research use only and supports laboratory investigation of relaxin signaling pathways, neuropeptide receptor distribution, and related GPCR pharmacology studies in neuroscience and endocrinology research.