Anti-RUVBL2 Antibody

RUVBL2, also called Reptin, is an ATP-dependent helicase belonging to the AAA+ family and forms part of chromatin-remodeling complexes such as INO80 and TIP60. This rabbit polyclonal antibody from Antibodies.com is raised against human RUVBL2 and cross-reacts with mouse and rat orthologs, enabling multi-species studies. Supplied as 200 µl of unconjugated IgG in a single-use vial, the reagent is validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation workflows. Investigators in fields including DNA damage response, transcriptional regulation, and cancer biology use this reagent to pull down endogenous Reptin from whole-cell lysates, localize it by immunostaining in tissue sections, and probe its interactions with partners such as INO80 subunits. For best stability, aliquot upon arrival and freeze at -20°C; avoid repeated freeze-thaw cycles to preserve binding activity over long-term storage. The polyclonal format recognizes multiple epitopes on the target, improving tolerance to minor cross-species sequence variation and supporting consistent signal in IP and co-IP experiments.