Anti-RUNX2 Antibody

RUNX2 is a master regulator of osteoblast differentiation and bone formation, acting as the essential transcription factor that drives mesenchymal precursor cells toward a skeletal lineage.

This polyclonal reagent from Antibodies.com was raised in rabbit against the human RUNX2 protein and is supplied as 100 µl of unconjugated antiserum in a single-use vial, ready for western blot, immunohistochemistry, and ELISA workflows.

Researchers investigating osteogenesis, chondrogenesis, and related developmental pathways rely on RUNX2 detection to track differentiation status, map tissue-level expression in developing bone, and probe the molecular basis of cleidocranial dysplasia and other skeletal disorders.

The antibody is validated on human and mouse samples, supporting cross-species studies in murine disease models and clinical tissue specimens.

For best results, aliquot upon arrival and store at -20 °C in working volumes to limit freeze-thaw cycles; the reagent remains stable for short-term use at 4 °C. Each vial is intended for research use only and should be handled with standard laboratory cold-chain precautions to preserve binding activity.