Anti-RUNX1T1 Antibody

Raised in rabbit against the transcriptional co-repressor RUNX1T1, this unconjugated polyclonal IgG primary antibody from Antibodies.com detects endogenous levels of total RUNX1T1 protein in human, mouse, and rat samples. Validated for Western blot, the reagent is supplied as a 100 µl vial of antigen-affinity-purified antiserum, allowing investigators to pair it with HRP, biotin, or fluorophore conjugates of their own choosing.

The polyclonal format recognizes multiple epitopes across the NHR1–NHR4 nervy homology regions of RUNX1T1, supporting studies that distinguish full-length RUNX1T1 from truncated AML1-ETO (RUNX1-RUNX1T1) fusion products generated by the t(8;21)(q22;q22) translocation common in acute myeloid leukemia research. Typical applications include characterizing expression in hematopoietic cell lines and primary leukemic blasts, validating knockdown or overexpression constructs, and probing normal versus aberrant transcriptional repressor complexes during hematopoiesis.

For continuous use, store at -20°C and limit freeze-thaw cycles by preparing working aliquots.