Anti-RUNX1 Antibody

This rabbit polyclonal antibody targets RUNX1, a transcription factor central to definitive hematopoiesis and one of the most frequently mutated genes in acute myeloid leukemia research. Supplied at 100 µL per vial in an unconjugated format, the reagent is validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation workflows using human, mouse, and rat samples. Because polyclonal antibodies recognize multiple epitopes on the target protein, they are commonly chosen for detecting RUNX1 splice isoforms, post-translational modifications, and fusion partners such as RUNX1-ETO (AML1-ETO). For storage, aliquot the antibody upon arrival and keep frozen at -20 °C; repeated freeze-thaw cycles should be avoided to preserve binding activity. The host species is rabbit, and the antibody is provided as a single-use vial suitable for chromatin immunoprecipitation, transcription factor mapping, and studies of leukemogenesis, platelet biology, and transcriptional regulation in hematopoietic stem cells. Antibodies.com distributes this primary antibody as part of its transcription factor reagent line.