Anti-RUFY2 Antibody

RUFY2 is a RUN-and-FYVE domain-containing scaffolding protein involved in early endosomal organization, where its FYVE domain binds phosphatidylinositol 3-phosphate and it acts as part of Rab5-associated membrane trafficking machinery. This polyclonal reagent from Antibodies.com is raised in rabbit against the human RUFY2 target and is supplied as an unconjugated IgG in a 100 µl vial, ready for direct use in immunoblotting and immunohistochemistry workflows.

The antibody has been validated for reactivity against human, mouse, and rat samples. Confirmed applications include western blot (WB) and immunohistochemistry (IHC). As an unconjugated IgG preparation, it can be paired with secondary reporters of choice, including HRP-, fluorophore-, or biotin-conjugated anti-rabbit secondaries, allowing flexibility across chemiluminescent, fluorescence, or chromogenic detection platforms. The polyclonal format is well suited to recognizing multiple epitopes across the RUN, FYVE, and central coiled regions characteristic of this endosomal scaffold.

For routine handling, store this liquid polyclonal IgG at 4 °C; for longer-term storage, aliquot and freeze at -20 °C to limit freeze-thaw damage to the antibody. Research use only.