Anti-RTN4 Antibody

This unconjugated rabbit polyclonal antibody targets RTN4 (Reticulon 4), a membrane-associated protein best known in neuroscience for its role as a neurite outgrowth inhibitor, and is supplied by Antibodies.com as a 100 µl liquid aliquot.

RTN4, also referred to as Nogo, is expressed in multiple isoforms (Nogo-A, Nogo-B, and Nogo-C) with distinct tissue distributions, including central nervous system myelin, endothelial cells, and several peripheral tissues. The reagent was raised in rabbit and validated for Western blot (WB) and immunohistochemistry (IHC) workflows, with demonstrated reactivity against both Human and Mouse samples.

Researchers studying CNS regeneration, myelin-associated inhibitory signaling, or vascular and ER-shaping biology apply this reagent to detect endogenous RTN4 in tissue sections and whole-cell lysates. Its unconjugated format allows users to pair it with their preferred secondary antibody and detection chemistry, supporting flexibility across fluorescence, chromogenic, and chemiluminescent readouts.