Anti-RTCD1 Antibody

RTCD1 (RNA terminal phosphate cyclase domain 1) is a conserved nuclear enzyme that catalyzes ATP-dependent conversion of RNA 3'-monophosphate termini into 2',3'-cyclic phosphodiester intermediates, a step implicated in tRNA maturation, end-turnover of broken RNA fragments, and broader RNA quality-control pathways. This rabbit polyclonal reagent from Antibodies.com is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, and the unconjugated antibody has been validated for western blot and immunohistochemistry across human, mouse, and rat samples. Each 100 µl vial is intended for laboratory research use, enabling detection of endogenous RTCD1 protein in lysates and tissue sections prepared from common mammalian model systems. For handling, store refrigerated at 4 °C, protect from light, and aliquot upon first use to limit freeze-thaw cycles and preserve immunoglobulin activity over time. The reagent supports investigations of post-transcriptional gene regulation, nuclear RNA processing machinery, and comparative studies of cyclase-domain enzyme function in vertebrate cells.