Anti-RRS1 (R286) Antibody

RRS1 (Ribosome Biogenesis Regulator 1) is a nuclear protein essential for 60S ribosomal subunit maturation and rRNA processing in eukaryotic cells. This rabbit polyclonal antibody, raised against a synthetic peptide encompassing residue R286 of human RRS1, is supplied by Antibodies.com as an unconjugated reagent for research use only. The immunogen region corresponds to a stretch conserved across mammalian orthologues, supporting reactivity with human, mouse, and rat samples.

The antibody is formulated at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide as a preservative at approximately pH 7.2, and is dispensed as a 50 µl vial. Validated applications include Western blot (WB) for detection of endogenous RRS1 in whole-cell lysates and immunohistochemistry (IHC) on formalin-fixed paraffin-embedded tissue sections. Western blot data resolves the expected band near 41 kDa, matching the predicted molecular weight of full-length human RRS1.

RRS1 has been linked in published studies to ribosome assembly, cellular proliferation, and ER stress response pathways, making this reagent useful for cancer cell biology, haematopoietic stem cell research, and investigations into disorders of ribosomal biogenesis. For handling, refrigerate the vial for short-term use, aliquot upon first thaw, and store at -20 °C for long-term preservation, avoiding repeated freeze-thaw cycles to maintain antibody activity.