Anti-RRN3 Antibody

This rabbit polyclonal antibody targets human RRN3, the RNA polymerase I-specific transcription initiation factor (also known as TIF-IA) that bridges Pol I with the rDNA promoter and drives pre-rRNA synthesis in the nucleolus. Supplied by Antibodies.com as an unconjugated IgG in a 200 µl vial, the reagent is validated for Western blot detection of endogenous RRN3 in human cell and tissue lysates, supporting studies of ribosome biogenesis, cell growth regulation, and nucleolar stress responses. The polyclonal format provides multiple epitope recognition for robust signal on the full-length RRN3 protein, and the unconjugated formulation allows flexible pairing with HRP, fluorophore, or biotin secondary reagents chosen by the user. Recommended for research use only in molecular biology and cancer research laboratories investigating Pol I transcription dynamics, p53-dependent nucleolar surveillance pathways, and the link between rRNA production and proliferative signaling.