Anti-RPS6KB1 (phospho S411) Antibody

This rabbit polyclonal antibody from Antibodies.com detects RPS6KB1 (also called p70S6K or S6K1) when phosphorylated at serine 411, an autophosphorylation site that reports activation of the mTORC1 growth signaling axis. Supplied as 100 µl of unconjugated IgG in a liquid vial, the reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples, supporting studies of insulin signaling, translational control, and cancer cell proliferation. The phospho-specific reagent lets researchers distinguish active kinase from total RPS6KB1 pools and follow pathway inhibition after treatment with mTOR, PI3K, or Akt inhibitors. Aliquot upon receipt and store at -20 °C to preserve phospho-epitope binding; protect from light and avoid repeated freeze-thaw cycles. Intended for research use only, this antibody pairs cleanly with total RPS6KB1 or pS6 (Ser235/236) antibodies for pathway-level readouts in cell lysates and fixed tissue sections.