Anti-RPS6KB1 Antibody

RPS6KB1 (also known as p70 S6 kinase or S6K1) is a serine/threonine kinase central to mTOR-dependent regulation of protein synthesis, cell growth, and survival. The polyclonal antibody offered by Antibodies.com is raised in rabbit against human RPS6KB1 and recognizes the target in human, mouse, and rat samples, supporting cross-species studies of translation control and metabolic signaling.

Validation data cover western blot detection of endogenous kinase, immunohistochemistry on tissue sections, and immunoprecipitation of native RPS6KB1 complexes from cell lysates. The reagent is supplied as 100 µl of unconjugated antiserum, allowing flexible secondary antibody pairing and direct labeling for custom detection workflows.

Recommended handling includes brief centrifugation before use, aliquoting to limit freeze-thaw exposure, and storage at -20 degrees C in working volumes; avoid repeated freeze-thaw cycles to preserve epitope recognition across long-term studies.