Anti-RPS6KA5 Antibody

Antibodies.com offers this rabbit polyclonal antibody raised against RPS6KA5, also known as MSK1 (Mitogen- and Stress-activated protein Kinase 1), a nuclear serine/threonine kinase that sits downstream of the MAPK and SAPK pathways. The unconjugated IgG reagent is validated for Western Blot detection of the human target and is supplied as 100 µl of ready-to-use solution. Because RPS6KA5 phosphorylates transcription factors such as CREB and ATF1 in response to cellular stress and growth factor signaling, this reagent is widely used in signaling and chromatin research, including studies of immediate-early gene regulation, histone H3 phosphorylation, and nuclear responses to UV or oxidative stress. Researchers commonly apply it to whole-cell lysates from human cell lines to probe endogenous kinase levels, activation-associated phosphorylation events, or changes in MSK1 expression under different stimulation states. Store refrigerated and protect from repeated freeze-thaw cycles to preserve antibody activity; aliquot upon first thaw if extended storage is needed. The reagent is intended for research use only and arrives as a primary antibody in liquid format compatible with standard immunoblotting workflows.