Anti-RPS4X Antibody

Targeting the X-linked ribosomal protein S4 (RPS4X), this polyclonal reagent from Antibodies.com is raised in rabbit and validated for Western blot and immunocytochemistry applications. RPS4X is a core component of the small 40S ribosomal subunit, encoded on the X chromosome, with a Y-linked paralog (RPS4Y) making it useful as a control for studies of sex chromosome dosage and ribosome heterogeneity.

The antibody reacts with endogenous RPS4X in human, mouse, and rat samples, making it relevant to cross-species investigations of translation, ribosome biogenesis, and ribosomal protein-related disorders such as Diamond-Blackfan anemia. Researchers also employ RPS4X detection when probing p53/MDM2 pathway crosstalk, since excess RPS4X binds MDM2 and helps stabilize p53.

Supplied unconjugated at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, the 100 µl vial format supports multiple staining runs and accommodates both standard immunoblotting and cell-based imaging protocols. The polyclonal pool recognizes multiple epitopes on RPS4X, providing robust signal across denaturing and fixed-cell conditions. Store refrigerated; protect from light; avoid freeze-thaw cycles to preserve activity.