Anti-RPS3 Antibody

RPS3 (Ribosomal Protein S3) is a highly conserved constituent of the small 40S ribosomal subunit involved in ribosome assembly and messenger RNA translation. Beyond its canonical role in protein biosynthesis, the protein carries extraribosomal functions that include participation in base excision repair of oxidative DNA lesions, modulation of NF-κB-driven transcription, and regulation of apoptotic signaling cascades.

The recombinant rabbit monoclonal reagent from Antibodies.com is supplied as a 100 µl unconjugated preparation in TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. It has been validated for western blot, immunocytochemistry, and immunohistochemistry workflows and shows reactivity against human, mouse, and rat samples, enabling cross-species comparative studies of ribosomal function and cellular stress responses.

This primary antibody is intended for research use only. It supports investigations of ribosomal biogenesis, the oxidative DNA damage response, innate immune signaling through NF-κB, and altered RPS3 expression patterns reported in oncology and neurodegeneration models.