Anti-RPS19BP1 Antibody

Polyclonal rabbit primary antibodies raised against ribosomal protein S19-binding protein 1 (RPS19BP1) provide a targeted reagent for studies of 40S ribosomal subunit biogenesis and pre-rRNA processing. The Antibodies.com Anti-RPS19BP1 Antibody is supplied at 1 mg/ml in phosphate buffered saline (pH 7.3) with 0.05% sodium azide, packaged as a 100 µl vial.

The reagent is unconjugated and validated for Western blot detection of endogenous RPS19BP1 in human, mouse, and rat sample backgrounds, supporting cross-species analysis of ribosome assembly pathways. RPS19BP1 acts within the Imp4/Impα complex, partnering with RPS19 to drive 18S rRNA maturation, and biallelic variants in the gene have been linked to Diamond-Blackfan anemia and related congenital bone marrow failure syndromes. Researchers investigating erythropoietic stress signaling, p53-independent ribosomal stress responses, and dyserythropoietic phenotypes incorporate this reagent into whole-cell lysate and nuclear extract workflows.

Format and handling notes: as a polyclonal preparation in PBS, the product is aliquot-ready for routine immunoblotting. Working stocks should be stored refrigerated and protected from light, with 0.05% sodium azide acting as a microbial preservative. Typical Western blot loading of 20 to 40 µg of total protein per lane resolves the approximately 15 kDa RPS19BP1 target, and the rabbit host pairs with standard anti-rabbit IgG HRP conjugates for chemiluminescent detection.