Anti-RPS19 Antibody

Produced in rabbit as a polyclonal reagent raised against the ribosomal protein S19 target, this unconjugated primary antibody from Antibodies.com is supplied at 100 µl per vial and validated for Western blot and immunohistochemistry workflows on human samples. RPS19 encodes a component of the small 40S ribosomal subunit that is essential for 18S rRNA maturation and proper ribosome assembly; loss-of-function mutations in the gene are a well-established cause of Diamond-Blackfan anemia, a rare congenital erythroid aplasia, making the protein a frequent subject of studies into ribosome biogenesis, hematopoiesis, and p53-dependent stress responses. Researchers also investigate RPS19 in the context of innate immunity because the protein is released during apoptosis and can act as a chemoattractant for monocytes. The polyclonal format increases the likelihood of recognizing multiple epitopes across the target, supporting applications such as expression profiling in patient-derived cells, characterization of ribosomal assembly intermediates, and immunostaining of fixed tissue sections used to map erythroid developmental defects and ribosomal stress phenotypes in model systems.