Anti-RPS16 Antibody

Ribosomal protein S16 is a core component of the 40S small ribosomal subunit, required for assembly of the mature ribosome and for cytoplasmic protein translation. Anti-RPS16 Antibody from Antibodies.com is a rabbit polyclonal reagent raised against this target, validated for Western blot, immunohistochemistry, and immunofluorescence workflows in human, mouse, and rat samples.

The antibody is supplied as 100 µl of unconjugated IgG at 1 mg/ml, formulated in PBS containing 0.1% sodium azide as a microbial preservative and 50% glycerol for stability at frozen storage temperatures. Researchers should aliquot upon arrival and avoid repeated freeze-thaw cycles to preserve antibody activity over time.

Validated applications include Western blot analysis of whole-cell lysates, where RPS16 detection can support normalization as a housekeeping ribosomal marker. Immunohistochemistry and immunofluorescence benefit from the unconjugated format, enabling flexible pairing with secondary antibodies of the researcher's choice, while established reactivity covers mouse, rat, and human RPS16. The RPS16 gene has clinical relevance in Diamond-Blackfan anemia, where haploinsufficiency of ribosomal proteins disrupts erythroid development, extending this reagent's utility into ribosomopathy and hematological research.