Anti-RPS14 Antibody

The RPS14 gene encodes ribosomal protein S14, an essential constituent of the 40S ribosomal small subunit that participates in cytoplasmic protein translation. RPS14 also localizes to the nucleolus, where it contributes to rRNA processing and ribosome biogenesis. Haploinsufficiency of RPS14, caused by interstitial deletions on chromosome 5q, is mechanistically linked to the 5q- subtype of myelodysplastic syndrome, making this protein a frequent subject of hematology and ribosomopathy research.

This rabbit polyclonal antibody from Antibodies.com is raised against RPS14 and validated for western blot and immunofluorescence workflows. It recognizes the endogenous protein in human, mouse, and rat samples, supporting use across standard cell line and primary tissue lysates as well as fixed cells for imaging studies. The unconjugated format allows laboratories to couple the antibody to their preferred fluorophore, biotin, or enzyme for tailored downstream detection. The reagent is supplied as a 100 µl volume and should be stored refrigerated to preserve binding activity across multiple experimental rounds.