Anti-RPS12 Antibody

This rabbit polyclonal antibody from Antibodies.com specifically recognizes ribosomal protein S12 (RPS12), a core component of the eukaryotic 40S ribosomal subunit. The unconjugated reagent is validated for Western blot and immunofluorescence on human samples and serves as a primary tool for studies of ribosomal biogenesis, translational control, and ribosome-associated disease mechanisms.

RPS12 sits near the decoding center of the small ribosomal subunit and contributes to translation fidelity. Published work has used RPS12-targeting antibodies to monitor shifts in ribosome composition during cellular stress, probe ribosomal assembly intermediates, and investigate haploinsufficiency phenotypes tied to Diamond-Blackfan anemia and related ribosomopathies. In immunofluorescence, the antibody can be applied to visualize cytoplasmic ribosome distribution and nucleolar incorporation pathways.

Supplied as 100 µl of polyclonal serum, the reagent is compatible with standard WB and IF protocols, and the rabbit host allows pairing with widely available secondary antibodies. Researchers studying ribosomal RNA processing, translation regulation, or ribosomal protein mutations will find this reagent a useful addition to their workflow.