Anti-RPL5 Antibody

The Antibodies.com polyclonal rabbit antibody targets RPL5, a highly conserved ribosomal protein of the large 60S subunit that supports ribosome biogenesis and assembles into cytoplasmic ribonucleoprotein complexes. Raised in rabbit and supplied as an unconjugated antiserum, this reagent is validated across three independent workflows: western blot, immunohistochemistry, and immunofluorescence, allowing researchers to track endogenous RPL5 expression in both fixed sections and freshly lysed samples.

The antibody was raised against a region of human RPL5 and reacts with mouse and rat orthologs as well, making it useful for cross-species studies of ribosome assembly, translational control, and stress-response signaling such as the MDM2-p53 axis, where RPL5 contributes as a regulatory factor. Diamond-Blackfan anemia researchers and those studying nucleolar stress or ribosomopathies will find this reagent a practical tool for monitoring RPL5 levels in cell culture lysates and tissue sections. Each vial contains 100 µl of liquid antibody; for long-term storage, freeze aliquots at -20 °C and protect from light to preserve activity across multiple freeze-thaw cycles.