Anti-RPL35A Antibody

This polyclonal reagent from Antibodies.com targets the 60S ribosomal subunit protein RPL35A, an essential component of the translation machinery that has been linked to Diamond-Blackfan anemia when mutated. Raised in rabbit and supplied as an unconjugated 100 µL aliquot, the antibody is validated for Western blot and immunohistochemistry applications on human samples. RPL35A (Ribosomal Protein L35a) resides on chromosome 3q29 and contributes to ribosome biogenesis; deficiencies in this protein have been shown to activate p53-dependent pathways in erythroid progenitor cells. Researchers studying ribosomal assembly, congenital bone marrow failure syndromes, hematopoiesis, or translation regulation can use this reagent to probe endogenous RPL35A expression in tissue sections and whole-cell lysates. Storage at -20 °C in working aliquots is recommended to preserve performance across multiple freeze-thaw cycles.