Anti-RPL3 Antibody

RPL3 encodes the ribosomal protein L3, a constituent of the 60S large subunit positioned near the peptidyl transferase center where it influences translation fidelity and ribosome assembly. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com is raised against epitopes conserved between human and mouse orthologs, supporting both Western blot analyses of whole-cell lysates and immunohistochemistry on formalin-fixed paraffin-embedded tissue.

Anticipated applications include probing ribosome biogenesis, characterising ribosomal stress responses, examining nucleolar morphology, and studying the contribution of L3 to p53-mediated signaling pathways under conditions of ribosomal perturbation. The 100 µL liquid format is supplied ready for dilution into blocking or antibody buffer; for long-term storage at -20 °C, small working aliquots are recommended to limit freeze-thaw cycles and preserve binding activity.

Validated for research use only, the antibody is a useful tool for investigators working on translation control, ribosomopathies, and proliferation in mammalian systems, including studies that compare baseline and perturbed ribosomal protein levels across cell lines and primary tissue.