Anti-RPL14 Antibody

RPL14 is a ribosomal protein that forms part of the 60S large subunit, where it contributes to ribosome biogenesis and cytoplasmic protein synthesis. Produced in rabbit as a polyclonal reagent, this unconjugated antibody from Antibodies.com recognizes the endogenous human, mouse, and rat RPL14 protein across multiple experimental readouts.

The antibody is supplied as 100 µl of liquid at 1 mg/ml in PBS supplemented with 0.1% sodium azide and 50% glycerol, a cryoprotective formulation that supports short-term refrigerated storage and longer-term freezing at -20 °C. Aliquoting upon first use is recommended to limit freeze-thaw cycles of the glycerol-stabilized stock.

Validated applications include western blot detection of RPL14 in cell lysates, immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, and immunofluorescence staining of cultured cells. The polyclonal host response yields recognition of multiple epitopes across the target, which is useful when probing conserved ribosomal components or comparing expression patterns between species. RPL14 has been investigated in ribosomopathy research and in the context of p53 pathway modulation, making this reagent relevant for studies of ribosomal protein function and cellular stress responses.