Anti-RPL11 Antibody

This rabbit polyclonal antibody from Antibodies.com targets ribosomal protein L11 (RPL11), a constituent of the large 60S ribosomal subunit that also operates as an extraribosomal regulator of the MDM2-p53 tumor suppressor pathway. Supplied at 1 mg/ml in phosphate buffered saline (pH 7.2) with 0.05% sodium azide, the unconjugated reagent is validated for Western blot and immunocytochemistry across human, mouse, and rat samples, supporting studies of ribosome biogenesis, nucleolar stress signaling, and p53-dependent growth arrest in oncology and ribosomopathy models.

The 100 µl vial provides enough material for multiple blots and staining experiments; store refrigerated, protect from light, avoid repeated freeze-thaw cycles, and aliquot working dilutions before long-term storage. As a polyclonal reagent, it recognizes multiple epitopes on RPL11, giving robust signal for endogenous protein detection in cell lysates and fixed cell preparations. Researchers investigating Diamond-Blackfan anemia, ribosomal protein haploinsufficiency, c-Myc-driven translational control, or nucleolar disruption pathways can monitor RPL11 steady-state levels and redistribution following ribosome biogenesis inhibitors using this reagent.