Anti-RPAP3 Antibody

Rabbit polyclonal antibody raised against RPAP3 (RNA Polymerase II Associated Protein 3), supplied by Antibodies.com as an unconjugated, azide-preserved liquid at 1 mg/ml in phosphate buffered saline (pH ~7.2). The 100 µl format is intended for Western Blot detection of endogenous RPAP3 in human, mouse, and rat samples.

RPAP3 functions as a scaffold within the R2TP complex, bridging HSP90 chaperone activity to the assembly of box C/D small nucleolar ribonucleoproteins and to the maturation of RNA polymerase II. Research use only applications include probing co-immunoprecipitation partners such as PIH1D1, RUVBL1, and RUVBL2, tracking stress-responsive chaperone-client interactions, and characterizing snoRNP biogenesis defects in cancer cell lines.

As a polyclonal reagent, the antibody recognizes multiple epitopes across the target, supporting detection at variable expression levels. Aliquot upon first use to minimize freeze-thaw cycles and preserve reactivity across long-term refrigerated storage.