Anti-RPA70 Antibody

Recognizing the 70 kDa subunit of Replication Protein A (RPA), this unconjugated mouse monoclonal IgG2a reagent from Antibodies.com supports research into DNA replication, nucleotide excision repair, mismatch repair, and homologous recombination.

Supplied as a 100 µl vial and validated for Western blot, immunocytochemistry, and immunoprecipitation, the antibody detects endogenous RPA70 across human, monkey, mouse, and rat samples.

Researchers studying replication stress and the DNA damage response use immunoprecipitation of native RPA complexes from nuclear extracts to characterize ssDNA-binding dynamics and S-phase checkpoint activation, while immunocytochemistry reveals RPA70 foci formation following genotoxic insult.

Western blot workflows allow monitoring of chromatin-associated RPA during replication fork stalling and recovery experiments, making this clone a practical tool for genome stability and cell cycle studies where cross-species comparison matters.