Anti-RPA3 Antibody

RPA3 (Replication Protein A3) is the 14 kDa subunit of the heterotrimeric Replication Protein A complex, the primary single-stranded DNA-binding protein in eukaryotic cells. This unconjugated rabbit polyclonal IgG antibody from Antibodies.com recognizes the RPA3 subunit and is validated for Western blot and immunofluorescence applications across Human, Mouse, and Rat samples.

Researchers working on DNA damage response, replication stress, homologous recombination repair, and checkpoint signaling rely on anti-RPA3 reagents to monitor RPA loading onto stalled replication forks and resected DNA ends. The polyclonal format increases the likelihood of recognizing multiple epitopes on the 14 kDa target, supporting consistent detection in denatured lysates by immunoblotting and in fixed cells by immunofluorescence imaging.

The reagent is supplied as a 100 µL liquid aliquot in an unconjugated format, allowing end users to couple it directly to fluorophores or enzymes for custom assay development. Aliquot upon receipt to limit freeze-thaw cycles and preserve long-term antibody activity for ongoing research use only studies.