Anti-RPA1 Antibody

Produced by Antibodies.com, this rabbit polyclonal antibody targets RPA1 (Replication Protein A1), a single-stranded DNA-binding protein essential for DNA replication, repair, and recombination. RPA1 forms a heterotrimeric complex with RPA2 and RPA3 and binds ssDNA with high affinity to stabilize unwound strands during S-phase and at stalled replication forks. The unconjugated reagent recognizes the human, mouse, and rat orthologs, supporting cross-species studies of genome maintenance and DNA damage response pathways. Researchers apply it in Western blot and immunofluorescence workflows to detect endogenous RPA1 in cultured cell lines, tissue sections, and primary cells, commonly following genotoxic stress such as UV irradiation or hydroxyurea treatment. Each vial contains 100 µl of antibody suitable for multiple immunoblots and staining experiments.