Anti-Rock2 Antibody

This rabbit polyclonal reagent from Antibodies.com recognizes Rho-associated coiled-coil containing protein kinase 2 (Rock2), a serine/threonine kinase operating downstream of RhoA GTPase. Rock2 governs actomyosin contractility, stress fiber assembly, focal adhesion turnover, and cell migration, making it a frequent subject in cytoskeletal remodeling, smooth muscle biology, and signal transduction research. The antibody is validated for Western blot across human, mouse, and rat samples, supporting comparative analysis of Rock2 expression in cell lines, primary cultures, and tissue lysates. Supplied as 50 µl of a 1 mg/ml stock in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2, the unconjugated preparation allows flexible assay design, including immunoprecipitation protocols, blocking peptide competition, and downstream detection with HRP- or fluorophore-conjugated secondary reagents. For extended projects, aliquot upon arrival into single-use portions to limit freeze-thaw cycles and preserve antibody activity.