Anti-Rock2 Antibody

Rho-associated coiled-coil kinase 2 (Rock2) is a serine/threonine kinase acting downstream of RhoA to regulate actin cytoskeleton dynamics, focal adhesion turnover, and stress fiber formation in eukaryotic cells. This unconjugated rabbit polyclonal antibody from Antibodies.com recognizes Rock2 and is validated for Western blot detection of the endogenous protein in human, mouse, and rat samples. Supplied as 100 µl of affinity-purified reagent at 1 mg/ml in phosphate buffered saline (pH 7.2) with 15 mM sodium azide as preservative, the antibody supports studies of smooth muscle contraction, cell migration, neurite outgrowth, and signaling pathways implicated in fibrosis, cardiovascular remodeling, and cancer cell invasion. The polyclonal format increases the likelihood of recognizing multiple epitopes on Rock2, improving detection across denatured lysate preparations. Aliquot upon receipt to limit freeze-thaw cycles, store refrigerated, and protect from light to preserve reagent activity. The unconjugated preparation gives researchers full flexibility to choose HRP, fluorophore, or biotin secondary detection reagents tailored to their Western blot workflow.