Anti-RNPC3 Antibody

Produced in rabbit as an unconjugated IgG polyclonal reagent, this Antibodies.com preparation specifically recognizes the RNPC3 subunit of the minor U12-type spliceosome, the ribonucleoprotein complex that excises a rare class of AT-AC introns from eukaryotic pre-mRNAs. Raised against recombinant human RNPC3, the antibody detects endogenous levels of total RNPC3 and reacts with samples from human, mouse, and rat origin, making it a practical choice across cell culture models and primary tissue from common laboratory species.

Supplied at 1 mg/mL in a 50 µL vial, the reagent is validated for western blot detection of whole-cell lysates and tissue extracts. Recommended handling includes storage at -20 °C in single-use aliquots to limit freeze-thaw cycles; thaw on ice immediately before each assay. Researchers investigating minor intron splicing, retinal development pathways in mouse models, and broader RNA-processing mechanisms can apply this reagent to confirm expression of the RNA recognition motif-containing splicing factor across compatible sample types.