Anti-RNF126 Antibody

RNF126 (Ring Finger Protein 126) is an E3 ubiquitin ligase that participates in cellular protein quality control, including the ubiquitination and disposal of misfolded glycoproteins via ER-associated degradation. This rabbit polyclonal IgG antibody from Antibodies.com is raised against endogenous RNF126 and is validated for Western blot and immunohistochemistry applications across human, mouse, and rat samples. Supplied as an unconjugated reagent in a 100 µL volume, the antibody can be applied directly to lysate or tissue preparations without secondary-label interference, supporting chromogenic staining workflows. Researchers studying T-cell receptor signaling, cancer cell proliferation, and proteasome-dependent turnover pathways use anti-RNF126 reagents to probe substrate recognition and post-translational regulation in mammalian systems. For storage, aliquot the antibody upon arrival and store at -20 °C in a frost-free freezer; avoid repeated freeze-thaw cycles to preserve binding activity. Each lot is affinity-purified from rabbit serum and supplied at working concentration for direct use in immunoblotting or fixed-tissue staining protocols.