Anti-RNASE3 Antibody

This rabbit polyclonal antibody from Antibodies.com targets human RNASE3, also known as Eosinophil Cationic Protein (ECP), a single-chain ribonuclease that resides in the secondary granules of activated eosinophils and is released during degranulation. The unconjugated reagent is supplied as 100 µL of polyclonal serum and is validated for Western blot (WB) and immunohistochemistry (IHC) on human tissue and cell samples.

RNASE3 is widely used as a marker of eosinophil activation and is studied in the context of allergic inflammation, bronchial asthma, helminth infection, and hypereosinophilic conditions. Because the antibody is polyclonal, it binds multiple epitopes on the target, which is useful when working with denatured proteins in WB or with formalin-fixed, paraffin-embedded sections in IHC. The unconjugated format allows researchers to pair the reagent with their preferred secondary detection system, whether HRP-, biotin-, or fluorophore-based.

This Primary Antibody is intended for research use only and is reactive with human RNASE3. Researchers should refer to the lot-specific datasheet accompanying the product for recommended starting dilutions, sample preparation notes, and expected band or staining patterns before first use.