Anti-RNASE13 Antibody

Ribonuclease A family member 13 (RNASE13) belongs to the pancreatic-type ribonuclease superfamily and shows epididymis-enriched expression, with proposed roles in post-testicular sperm maturation and processing of extracellular RNA in the male reproductive tract. This unconjugated rabbit polyclonal reagent from Antibodies.com was raised against RNASE13 and is validated for western blot and immunohistochemistry on human samples, enabling tissue-level and protein-level studies of RNASE13 distribution in reproductive and other tissues.

The antibody ships as a 100 µL aliquot in liquid format and should be stored refrigerated for routine use or frozen for longer-term preservation of activity. For western blot, standard reducing SDS-PAGE conditions with HRP- or fluorophore-conjugated secondary antibodies work well; for immunohistochemistry, antigen retrieval on paraffin or cryosection preparations is recommended. The polyclonal format increases the likelihood of recognizing multiple epitopes on the relatively small RNASE13 protein, which can help when working with limited or partially degraded samples.

Investigators studying male reproductive biology, extracellular RNA metabolism, or comparative analysis of the RNase A family can apply this reagent to map expression across the epididymal epithelium, vas deferens, and other tissues, and to follow changes in RNASE13 abundance under experimental or clinical conditions.