Anti-RIPK2 Antibody

Rabbit polyclonal antibodies targeting RIPK2 (also called RIP2 or RICK), a CARD-containing serine/threonine kinase central to NOD1 and NOD2 innate immune signaling, are supplied by Antibodies.com as 100 µl of unconjugated reagent validated for western blot, immunohistochemistry, and immunofluorescence in human, mouse, and rat samples.

The polyclonal host response enables recognition of multiple epitopes on native and denatured target protein, supporting use in pathway studies of NF-κB and MAPK activation downstream of pattern-recognition receptor engagement. Applications extend to investigations of inflammatory signaling, autophagy cross-talk, and bacterial peptidoglycan responses relevant to inflammatory bowel disease and host-pathogen research models.

The unconjugated format permits flexible pairing with user-preferred fluorophores, biotin, or HRP secondary reagents, and the rabbit host allows straightforward co-staining on mouse and rat specimens. Aliquot upon receipt to limit freeze-thaw cycles and store refrigerated short term in the supplied vial format, which suits routine short-term experimental workflows. Researchers studying NLR family signaling or screening kinase substrates benefit from a reagent reactivity-tested across three common mammalian model systems.