Anti-RHPN1 Antibody

Rhophilin Rho GTPase binding protein 1 (RHPN1) functions as an intracellular effector of RhoA signaling and participates in actin cytoskeleton remodeling, with research interest in epithelial tumor biology and Rho GTPase pathway studies. The unconjugated rabbit polyclonal antibody available from Antibodies.com is raised against this target and is supplied as 200µl of liquid stock.

Validated for Western blot detection in human and mouse sample backgrounds, this polyclonal IgG reagent recognizes multiple epitopes across the RHPN1 protein. The polyclonal format can support immunoblotting of full-length RHPN1 as well as potential isoforms in lysate-based workflows.

Typical use cases include probing RHPN1 expression in cultured mammalian cell lines, primary tissue lysates from mouse models, and overexpression or knockdown experiments investigating RhoA-driven cytoskeletal phenotypes. Because the host species is rabbit, secondary detection can be paired with standard anti-rabbit HRP or fluorescent conjugates in standard immunoblotting protocols.

For handling, the antibody should be aliquoted upon receipt and stored refrigerated to limit repeated freeze-thaw cycles of the stock vial, preserving IgG activity over the reagent's shelf life.