Anti-RHOBTB3 (L365) Antibody

RHOBTB3 is a member of the Rho family of small GTPases, a group of signalling proteins that shape the actin cytoskeleton and direct vesicle trafficking through the Golgi. This unconjugated rabbit polyclonal reagent is raised against an internal epitope of human RHOBTB3 and is supplied by Antibodies.com as 100 µl of stock at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide, pH approximately 7.2. In western blot and immunohistochemistry workflows it detects endogenous protein in human and rat samples, with reactivity confirmed by the manufacturer for those two species. The polyclonal format allows simultaneous recognition of several epitopes on the target, which is helpful when mapping post-translational modifications or splice-variant patterns in tissue sections and cell lysates. Published work links RHOBTB3 to Golgi organisation, autophagy regulation and certain cancer pathways, so this antibody is a practical tool for cell biology, oncology and neuroscience projects that compare expression across disease models and matched controls. Working aliquots should be stored refrigerated and protected from light, and the reagent is intended for research use only.