Anti-RhoA Antibody

The RhoA protein, a member of the Ras homolog family of small GTPases, serves as a master regulator of actin cytoskeleton dynamics, influencing cell shape, migration, polarity, and contractility through downstream effectors such as Rho-associated kinase (ROCK). This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against RhoA and is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples. Supplied at a 100 µl volume, the polyclonal format offers recognition of multiple epitopes on the target, which can strengthen signal in tissue sections and whole-cell lysates.

Researchers studying cytoskeletal remodeling, focal adhesion turnover, Rho-GTPase-driven gene expression, or stress fiber formation commonly use this reagent in cell biology, oncology, neuroscience, and cardiovascular research applications. Because the antibody is unconjugated, investigators retain flexibility to pair it with HRP-, biotin-, or fluorophore-conjugated secondary reagents for chromogenic, fluorescent, or chemiluminescent detection depending on the experimental readout.