Anti-Rho A Antibody

The Rho family GTPase Rho A regulates actin cytoskeleton dynamics, cell migration, focal adhesion turnover, and cell cycle progression in eukaryotic cells. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against Rho A and detects the endogenous target in samples from human, mouse, and rat origin, supporting workflows in cytoskeletal biology, oncology signaling, and vascular research.

Supplied at 100 µL pack size, the antibody is routinely applied in Western blot, immunohistochemistry, and ELISA workflows, letting laboratories profile Rho A expression across tissue sections, whole-cell lysates, and conditioned samples. Polyclonal reactivity broadens epitope coverage compared with monoclonal alternatives, which is helpful for probing Rho A activation states and investigating pathway crosstalk with downstream effectors such as ROCK, mDia, and LIM kinase.

Common research applications include studying epithelial–mesenchymal transition in carcinoma models, mapping Rho GTPase signaling in neuronal development, and characterizing contractile responses in cardiovascular and smooth muscle studies. The unconjugated format offers flexibility to pair the reagent with a preferred fluorophore, biotin, or HRP label, integrating cleanly into custom imaging, pull-down, and plate-based detection protocols.