Anti-RGS3 Antibody

This rabbit polyclonal IgG antibody from Antibodies.com targets human RGS3 (Regulator of G-protein Signaling 3), an intracellular GTPase-accelerating protein that negatively modulates heterotrimeric Gα signaling downstream of G protein-coupled receptors. The unconjugated reagent is supplied as a 50 µl aliquot and is validated for Western blot detection of the endogenous protein in human lysates. RGS3 belongs to the B/R4 subfamily of RGS proteins and has been studied in the context of receptor desensitization, calcium signaling, and downstream effector pathways in multiple cell types.

Researchers using this reagent in western blot workflows typically resolve whole-cell or tissue extracts by SDS-PAGE, transfer to nitrocellulose or PVDF membranes, and probe with this polyclonal reagent followed by an appropriate anti-rabbit IgG secondary. The polyclonal format is intended to recognize multiple epitopes on RGS3, supporting detection across different isoforms where expression levels permit.