Anti-RGS22 Antibody

RGS22 belongs to the Regulator of G-protein Signaling (RGS) family of GTPase-activating proteins that dampen heterotrimeric Gα signaling. This Antibodies.com reagent is a rabbit polyclonal primary antibody raised against the human RGS22 protein and supplied as 100 µl of unconjugated antiserum. It is validated for Western blot and immunohistochemistry workflows and can be paired with HRP, fluorescent, or biotinylated secondary reagents.

RGS22 displays a tissue-restricted expression profile with notable presence in testis and several human cancer cell lines, where it has been examined as a candidate marker of spermatogenic function and tumor biology. Researchers can apply the antibody to lysates from cultured cells or tissue homogenates for Western blot detection, and to fixed paraffin-embedded or cryosectioned specimens for immunohistochemistry localization. Confirmed reactivity is with human RGS22.

Key attributes include rabbit host, polyclonal clonality, unconjugated format, and reactivity confirmed against the human target. The vial should be refrigerated on arrival and handled as small aliquots to limit freeze-thaw cycles of the stock. For research use only.