Anti-RGS17 Antibody

RGS17 (Regulator of G-protein Signaling 17) is a member of the RZ subfamily of RGS proteins that accelerate GTP hydrolysis on heterotrimeric G-protein alpha subunits. Aberrant RGS17 expression has been documented in non-small cell lung cancer and prostate adenocarcinoma tissues, where it contributes to tumor cell proliferation and survival signaling cascades.

This unconjugated rabbit polyclonal primary antibody from Antibodies.com is supplied as 100 µl of liquid reagent in a vial, validated for western blot (WB) and immunofluorescence (IF) workflows on human samples. The polyclonal format enables recognition of multiple epitopes on the RGS17 target, supporting detection of endogenous protein levels in cell lysates and fixed tissue sections.

Researchers studying G-protein coupled receptor biology and oncology signaling use this reagent to profile RGS17 expression across cancer cell line panels, examine Gα subunit regulation mechanisms, and explore downstream pathways linked to cell migration and invasion. Aliquot upon receipt and avoid repeated freeze-thaw cycles to preserve antibody activity.