Anti-RGS10 Antibody

This rabbit polyclonal antibody from Antibodies.com targets RGS10 (Regulator of G-protein Signaling 10), a GTPase-activating protein that accelerates GTP hydrolysis on Gα subunits and dampens GPCR-driven signaling cascades. The reagent is supplied as 100 µl of unconjugated antisera, validated for Western blot and immunohistochemistry on human samples, and is raised in rabbit to support multiple-round probing and flexible secondary antibody selection.

RGS10 plays an established role in dopaminergic neuron survival, microglial activation, and innate immune regulation, making antibodies against it useful for neuroscience and immunology laboratories studying Parkinson's disease models, neuroinflammation, or G-protein pathway dynamics. The polyclonal format increases the likelihood of recognizing multiple epitopes across the RGS10 protein, which is helpful when working with truncated isoforms or partial proteolysis products in tissue lysates.

As an unconjugated preparation, the antibody can be paired with HRP, biotin, or fluorophore-conjugated secondaries depending on the application, and is appropriate for chromogenic IHC on formalin-fixed paraffin-embedded sections as well as standard immunoblotting of cell and tissue extracts.